
DNA ligase - Wikipedia
DNA ligase ... DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
DNA Ligase- Definition, Structure, Types, Functions
Aug 3, 2023 · DNA replication, DNA repair, and recombinant DNA experiment are incomplete without DNA ligases. DNA ligases join the nicks and form a phosphodiester bond between the nucleotide.
What Does DNA Ligase Do? Function, Roles, and Uses
Aug 20, 2025 · DNA ligase catalyzes the formation of a phosphodiester bond, which effectively seals breaks or “nicks” in the DNA backbone. This bond forms between the 3′ hydroxyl end of one …
DNA Ligase - an overview | ScienceDirect Topics
DNA ligase is an enzyme that plays a crucial role in maintaining the structural integrity of the genome by repairing breaks in the DNA backbone. It catalyzes the formation of a bond between adjacent …
DNA Ligation: Mechanisms, Types and Applications | Danaher Life …
DNA ligation is the process of joining two strands or fragments of DNA molecules through a phosphodiester bond formed by the enzyme DNA ligase. DNA ligase is involved in maintaining the …
Dna ligase Definition - Cell Biology Key Term | Fiveable
DNA ligase is an essential enzyme that facilitates the joining of DNA strands by forming phosphodiester bonds between the 3' hydroxyl and 5' phosphate ends of adjacent nucleotides.
What is DNA Ligase? - RNA / BOC Sciences
DNA ligase is an enzyme that catalyzes the formation of phosphodiester bonds between adjacent DNA strands and plays an important role in DNA replication.
Molecule of the Month: DNA Ligase - RCSB: PDB-101
DNA ligase reconnects DNA strands when they are broken. It uses a cofactor molecule (shown in red) for power and a special lysine amino acid (shown in magenta) to perform the reaction.
What is DNA ligase? | IDT - Integrated DNA Technologies
Sep 6, 2023 · DNA ligase is an enzyme that catalyzes the formation of a covalent bond between a 5’ phosphate and a 3’ hydroxyl group at the termini of DNA fragments; this bond ligates the two DNA …
Ligase in Molecular Genetics - numberanalytics.com
May 26, 2025 · A comprehensive guide to ligase, its mechanism, types, and applications in molecular genetics, including DNA replication and repair.