A new study reveals how restoring α-synuclein levels can help preserve synaptic vesicle composition and function, offering ...

(3) This causes synaptic vesicles to fuse with the terminal membrane, releasing neurotransmitter into the gap between neurons, known as the synaptic cleft. (4) The neurotransmitters bind to ...

One technique used a tracer called [11C]UCB-J to assess levels of synaptic vesicle glycoprotein 2A (SV2A), a protein found in ...

which are accumulated inside the vesicles—they do not really measure synaptic transmission. The groups decided to create an FFN that targeted the neuronal vesicular monoamine transporter (VMAT ...

For example, the researchers showed that in physiological conditions, local variations in ATP can also affect the viscosity of the cytosol, of synaptic vesicles and of active zones in the ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ... the presynaptic neuron and restored inside a vesicle ready to be used again.