SportsLine's model simulated Seattle Seahawks vs. San Francisco 49ers 10,000 times and made its Week 11 NFL picks, ...

The 49ers (5-4) can parlay Christian McCaffrey’s encore into a pivotal NFC West win Sunday over the visiting Seattle Seahawks ...

Seattle Seahawks coach Mike Macdonald faced an unusual conundrum this week as he game-planned for Sunday's rematch with the ...

The San Francisco 49ers need a win in Week 11 over the Seattle Seahawks. Their injury situation may make it a significant ...

San Francisco head coach Kyle Shanahan discussed Friday the 49ers' offensive line ahead of a matchup with the Seattle ...

Preview the Week 11 matchup between the San Francisco 49ers and Seattle Seahawks with predictions, odds, over/under, spread, ...

Don’t expect the San Francisco 49ers to take their foot off the gas in their usage of running back Christian McCaffrey.

The 49ers definitely will be without defensive tackle Kevin Givens (groin), punter Mitch Wishnowsky (back) and cornerback ...

Two 49ers stars are questionable for San Francisco's NFC West showdown against the Seattle Seahawks on Sunday at Levi's ...

Left tackle Trent Williams’ ankle and wrist injuries could force him to miss his first 49ers game this season Sunday against ...

As part of this week's DFS slate, the Seahawks are scheduled to take the field against the 49ers. Which players from this ...

What to look for from the top Seahawks and 49ers players and how to watch the game as they face off on Sunday, week 11.