Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

George Kittle earlier made his team-high seventh touchdown catch. San Francisco 49ers wide receiver Deebo Samuels, middle, ...

NFL Week 11 odds, picks, predictions, TV and streaming information for the Sunday football game between the Seattle Seahawks ...

Former Oregon Ducks cornerback Deommodore Lenoir is now among the highest paid at his position in the National Football ...

Cornerback Deommodore Lenoir, who has emerged as a cornerstone of the defense, agreed to a five-year extension.

Not what the Tampa Bay Buccaneers were looking for on Sunday when they fell to the San Francisco 49ers 23-20 on a walk-off ...

The San Francisco 49ers (5-4) will square off against their NFC West-rival, the Seattle Seahawks (4-5) in a matchup on Sunday ...

San Francisco 49ers tight end George Kittle has two objectives for this season — remain healthy and win a Super Bowl.

Before their Week 11 matchup against the Seattle Seahawks, we'll be making our San Francisco 49ers bold predictions ...

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the Seattle Seahawks in Week 11 of ...

The San Francisco 49ers and Seattle Seahawks will face off in a NFC West showdown this Sunday, and if you want to attend the ...

SANTA CLARA, Calif. — The season debut of Christian McCaffrey helped make the San Francisco 49ers’ offence look more like it did a year ago than it did in an up-and-down first half of the season.