Many patent applicants currently face difficulty in obtaining antibody claims because of written description and enablement ...

Different types of antibodies are produced by your immune system. These five antibodies help fight disease by detecting viruses, bacteria, and other pathogens (disease-causing microorganisms) and ...

Intranasal vaccination is an attractive strategy for preventing COVID-19 disease as it stimulates the production of multimeric secretory immunoglobulin A (IgA), the predominant antibody isotype in the ...

Lastly, the authors used a competitive ELISA assay to show that multimerization could improve the neutralizing capacity of these antibodies. The strength of this paper is the cloning of multiple IgA ...

Now, with the acquisition of TigaTx, Epsilogen is adding that company's expertise and assets in therapeutic IgA antibodies to its arsenal. Wilson noted that IgA activates a type of immune cell called ...

a biotechnology company developing engineered immunoglobulin A (IgA) antibodies, to create the world’s leading pan-isotype cancer antibody company. As a result of the combination of these two ...

The move combines Epsilogen’s clinical focus on immunoglobulin E (IgE) antibodies with TigaTx’s work on immunoglobulin A (IgA), creating what the companies describe as a “pan-isotope” platform for ...

U.K.-based Epsilogen has bought Boston biotech TigaTx with the aim of creating “the world’s leading pan-isotype cancer antibody company.” Both companies are focused on immunoglobulin ...

The acquisition combines IgA antibody assets and expertise of Boston-based TigaTx with Epsilogen's assets and expertise in IgE to create the world's leading pan-isotype cancer antibody company ...

Data from a Phase I trial found it to be safe and well tolerated with early signs of clinical activity EPS 401 (formerly TIGA-001), an anti-EGFR IgA antibody with IND-enabling studies underway ...