This finding initiated decades of extensive immunochemical studies of immunoglobulin structure and function ... been used to study the regulation of IgA switching in Warren Strober's laboratory.

The antigen-binding site of the antibody has a unique structure that allows it to bind ... coated with host IgA, and that these IgA-coated BEV may activate CD89 + immune cells to aggravate ...

Its lead asset, JADE-001, targets the cytokine anti-A PRoliferation-Inducing Ligand (APRIL) for immunoglobulin A (IgA) nephropathy ... regarding the ownership structure of the combined company ...

Different types of antibodies are produced by your immune system. These five antibodies help fight disease by detecting viruses, bacteria, and other pathogens (disease-causing microorganisms) and ...

Structure of (A) IgG; (B ... (2003) Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12. Journal of ...

This second of four exclusive episodes explores whether sparsentan can leapfrog renin-angiotensin system (RAS) blockade and ...

Cancer scientists engineer a new type of antibody which could be used to boost the immune systems of patients fighting disease.

Some practitioners argue that method of treatment claims are easier to obtain for structure–function-defined antibodies, but recent USPTO prosecution histories show that these claims also face ...

Researchers used AI models to design antibodies that neutralize over 1,300 SARS-CoV-2 strains, including Delta and Omicron.

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines that target pathogens transmitted through the respiratory tract and may cause fatal infections ...

only the albumin-based intranasal vaccine gave rise to robust mucosal IgA antibody responses. The study thus suggests that this needle-free, albumin-based vaccine platform may be attractive for ...