Worries that tumor necrosis factor (TNF) inhibitors may exacerbate or even cause lung disease in patients with rheumatoid ...

New research confirms that specific herbal therapies—including turmeric, boswellia, and ashwagandha—can reduce joint ...

Whereas the trial's original primary analysis showed roughly double the MACE risk with tofacitinib as compared with TNF ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

Treatment groups included 16,417 JAKi courses, 35,373 tumor necrosis factor inhibitor courses, and 21,218 courses of biologic therapies with other mechanisms of action. Most person-time ...

The investigators were thus able to identify the cancer risk in a large national cohort of 6,366 patients with RA who first started treatment with TNF inhibitors between January 1999 and July 2006.

Led by AbbVie’s Humira, biologic TNF inhibitors transformed the treatment of autoimmune diseases over the past 20 years. However, the biologic modality can cause adverse effects and loss of ...

Treatment with tumor necrosis factor (TNF) inhibitors is associated with an increased risk of infection; however, the safety of continuing anti-TNF therapy during the period running up to surgery ...

Dr. Glass spoke about the Company’s small-molecule TNF-alpha (TNF-α) inhibitor, isomyosamine, which has shown potential for regulating pro-inflammatory cytokines associated with sarcopenia.

Schematic of TNF inhibitors and their mode of action. Receptor (i.e. etanercept, lenercept) and antibody based (i.e. infliximab, adalimumab, golimumab) anti-TNF biologics inhibit both solTNF and ...