Pronounced “soh-TIK-too,” SOTYKTU is a once-daily pill for adults with moderate to severe plaque psoriasis that works inside ...

inhibitors showed no increased incidence of major adverse cardiovascular events (MACEs) compared with those treated with tumour necrosis factor (TNF) inhibitors or biologic disease-modifying ...

The tumor necrosis factor (TNF) inhibitor certolizumab pegol (Cimzia) appears to significantly increase the survival rate for pregnancies complicated by antiphospholipid syndrome (APS), an ...

Led by AbbVie’s Humira, biologic TNF inhibitors transformed the treatment of autoimmune diseases over the past 20 years. However, the biologic modality can cause adverse effects and loss of ...

Hence, IL-23 is less systemic and more tissue specific than TNF inhibitors.” This translates into efficacy without the same risk for infections as TNF blockers, according to Hanauer.

One instance pertains to the black box warning for lymphoma in patients treated with TNF inhibitors. Although some of the pre-approval studies demonstrated significant risk, others did not.

Sanofi will halt the development of its oral tumour necrosis factor (TNF) inhibitor balinatunfib as a monotherapy after it failed to reach the primary endpoint in a Phase II trial. Preliminary ...

Tumor necrosis factor (TNF)-α inhibitors are associated with an increased risk of fungal infections, according to the findings of a systematic review published in Mycoses. Investigators explored ...

Among patients who were initiated on the tumor necrosis factor (TNF) inhibitor infliximab (Remicade), 55.3% of those receiving molecular medicine-informed guidance with insights from a real-time ...