Worries that tumor necrosis factor (TNF) inhibitors may exacerbate or even cause lung disease in patients with rheumatoid ...

New research confirms that specific herbal therapies—including turmeric, boswellia, and ashwagandha—can reduce joint ...

Whereas the trial's original primary analysis showed roughly double the MACE risk with tofacitinib as compared with TNF ...

However, “whereas TB [tuberculosis] used to be an issue with TNF inhibitors, it’s not really an issue after screening. It will probably be the same for JAK inhibitors when we start using the ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

Led by AbbVie’s Humira, biologic TNF inhibitors transformed the treatment of autoimmune diseases over the past 20 years. However, the biologic modality can cause adverse effects and loss of ...

Treatment groups included 16,417 JAKi courses, 35,373 tumor necrosis factor inhibitor courses, and 21,218 courses of biologic therapies with other mechanisms of action. Most person-time ...

One instance pertains to the black box warning for lymphoma in patients treated with TNF inhibitors. Although some of the pre-approval studies demonstrated significant risk, others did not.

The investigators were thus able to identify the cancer risk in a large national cohort of 6,366 patients with RA who first started treatment with TNF inhibitors between January 1999 and July 2006.

Treatment with tumor necrosis factor (TNF) inhibitors is associated with an increased risk of infection; however, the safety of continuing anti-TNF therapy during the period running up to surgery ...

Dr. Glass spoke about the Company’s small-molecule TNF-alpha (TNF-α) inhibitor, isomyosamine, which has shown potential for regulating pro-inflammatory cytokines associated with sarcopenia.