Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting ...

Led by Ryotaro Hashizume at Mie University, the research team demonstrated that CRISPR can be used to remove the extra copy of chromosome 21 - the fundamental cause of Down syndrome ...

Scientists in Japan have made a breakthrough using CRISPR technology to remove the extra chromosome responsible for Down ...

Specifically, the researchers found that intersectin keeps tiny, message-carrying bubbles inside brain cells in a particular ...

A new research paper, featured on the cover of Aging (Aging-US) Volume 17, Issue 6, was published on June 4, 2025, titled “DoliClock: a lipid-based aging clock reveals accelerated aging in ...

Japanese scientists may have rewritten the future of Down syndrome research by using gene editing to remove the extra ...

How does the CRISPR Down Syndrome breakthrough work to remove the extra chromosome 21? We are closer than ever to a world ...

In Canada, "the average lifespan of someone with Down syndrome is about 60 years old," said Dr. Brian Skotko, senior author ...

Research study examines Alzheimer's disease drug on tissue samples from people with Down syndrome The anti-amyloid drug lecanemab bound to amyloid plaques but also bound to blood vessels ...

The research team evaluated brain tissue samples from 15 people with Down syndrome who were between the ages of 43 and 68 years. The study was limited in its sample size and age range - in the ...

By age 30, most individuals with Down syndrome have abnormal clumps of amyloid in their brain, and many show signs of dementia in their 40s and 50s.

People with Down syndrome have a unique genetic predisposition: overexpression of the APP gene due to trisomy of chromosome 21 leads to overproduction of beta-amyloid (Aβ) protein, making them a ...