A new study reveals how restoring α-synuclein levels can help preserve synaptic vesicle composition and function, offering ...

This explainer outlines how neurons and glial cells coordinate electrical and chemical signals to form complex brain networks ...

Cellular communication is a critical process that relies on exocytosis, during which cells release stored chemical messengers contained within intracellular nanoscale vesicles (50–500 nm in diameter).

Buchmann Institute for Molecular Life Sciences, Goethe-University, Frankfurt am Main, Germany Institute for Biophysical Chemistry, Department of Biochemistry, Chemistry, and Pharmacy, ...

Engineered extracellular vesicles incorporating a viral fusogenic protein and bacterial intein enable efficient intracellular delivery of therapeutic proteins and RNA.

Here, we describe the isolation and structure determination of proteins in membrane vesicles derived directly from cells. Structures of the ion channel Slo1 from total cell membranes and from cell ...

ATP has been found to regulate cytosolic viscosity and thereby protein aggregation, which can lead to synaptic dysfunction and neurodegeneration. NMN (nicotinamide mononucleotide) is a precursor ...

Vesicles are small blisters that can appear on your skin. They can be a symptom of a medical issue or a sign of tissue injury. Some conditions, like contact dermatitis or cold sores, may not ...

Neuroscientists who have closely studied these alterations, known as "synaptic plasticity," have identified numerous molecular processes causing such plasticity. Yet an understanding of the "rules ...