A contributing factor underlying the AKT inhibitor ineffectiveness relates to how kinase inhibitors are developed. These methods include cell viability assays that indirectly report on inhibitor ...

We evaluated the effect of PTA on cell viability via the MTT assay. Addition of PTA at increasing concentrations (25, 50, 100, 200, 400 μM) maintained the cell viability of ∼100% after 24 h even with ...