The study created a supervised learning model that integrates explainable artificial intelligence (XAI) techniques to enhance clinical interpretability. Using data from 588 kidney transplant ...

3D animation depicting the anatomy and function of the distal convoluted tubule in the nephron, focusing on reabsorption, secretion, and regulation of electrolytes and pH balance. 3D animation ...

In contrast, activation of GR signalling with dexamethasone in human kidney organoids or mouse IMCD3 cells increases cilia length, an effect blocked by the GR antagonist RU486. Analysis of GR-null ...

After rank normalisation of biomarker distributions, between-group differences in their changes were assessed by multivariable-adjusted mixed model analysis of variance ... Finally, proteases active ...

Despite its strong correlation with kidney function decline, the causal role of fibrosis and its underlying molecular mechanisms remain poorly understood. We developed an Fbxw7-deletion-based mouse ...

Our group investigates health effects of ambient environmental exposures using advanced environmental epidemiological methods and geospatial modelling. Principle exposures of interest are air ...