CHICAGO, IL—A large-scale, randomized trial testing routine cerebral embolic protection during TAVI has once again failed to show the device reduces the risk of stroke. The two trials, which in ...

Routine use of devices to prevent cerebral emboli during transcatheter aortic valve implantation (TAVI) did not prevent strokes, a large randomized trial showed. Incidence of stroke within 72 hours ...

“In our population, a routine strategy of cerebral embolic protection did not reduce the rate of stroke. Our study provides convincing evidence that there is no value in the routine use of this ...

Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence ...

Cerebral embolic protection (CEP) devices are designed to stop this debris reaching the brain, and they have been suggested as a solution to reduce stroke risk for TAVI patients. However, evidence ...

Still, embolic protection continues to be deployed in at least some TAVI cases, possibly due to the lower rate of disabling stroke seen with the Sentinel device in PROTECTED TAVR and a subsequent ...

New research suggests cerebral embolic protection devices do not lower the risk of stroke in patients undergoing transcatheter aortic valve implantation.

The study was published online in JAMA Neurology on March 31, 2025.

"In these OAC-naive patients, asundexian was associated with a slight increase in stroke rates but demonstrated a lower risk ...

Approximately 45% of ischemic strokes are caused by small or large artery thrombus, 20% are embolic in origin, and others have an unknown cause (Hickey, 2003). Thrombosis can form in the ...