Background: Interleukin-17A (IL-17A) is the founding member of a novel family of inflammatory cytokines that plays ... IL-17A signals through its receptor, IL-17RA, which is expressed in many ...

The hypothalamus contains specialized cytokine receptors. These receptors concentrate in two key areas: the arcuate nucleus and preoptic area. These regions serve as control centers for reproductive ...

Consistent with greater sensitivity to proinflammatory signals, patients with more severe disease had higher expression of inflammatory cytokine receptors and signal transducers, and expression of ...

Koch Institute for Integrative Cancer Research, and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States The Broad Institute of ...

Manchester Institute of Biotechnology, School of Biological Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Princess Street, Manchester M1 7DN, U.K. Manchester ...

Poststroke cognitive impairment (PSCI) is a common residual disability after stroke, often underestimated and underdiagnosed. We previously found that ursodeoxycholic acid (UDCA), a host‐microbiota ...

One of the primary mechanisms of SCFA benefits was the direct activation of a group of G-protein-coupled receptors (GPCRs), termed free fatty acid receptors (FFARs), the FFAR2 (GPR43), and FFAR3 ...

1 Affiliated Hospital of Shandong Second Medical University, Weifang, China 2 Department of Hematology and Oncology, Shenzhen Children’s Hospital, Shenzhen, China Chimeric antigen receptor natural ...

We identify the fat body-derived cytokine, Upd2, in targeting and inducing JAK/STAT signaling in tracheal progenitors to maintain their directional migration. Perturbation of either Upd2 production in ...

Eight parameters (all blood tests for cytokines or cytokine receptors) were considered to be not available. Tables 4 (remission) and 5 (relapse) depict those items for which RMs achieved a consensus ...