During translation, which is the second major step in gene expression, the mRNA is "read" according to the genetic code, which relates the DNA sequence to the amino acid sequence in proteins ...

Scientists used IBM's R2 Heron quantum processor to predict the secondary protein structure of a 60-nucleotide-long mRNA sequence.

Previous studies have created language models to decode various biological sequences, including proteins and DNA, but this was the first language model to focus on the untranslated region of mRNA.

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...

One key benefit of synthetic DNA is that it enables flexible sequence design independent of any naturally occurring template. Methods for optimization of expression in a target organism will be ...

Self-amplifying mRNA vaccines include a special mRNA that replicates itself in the cell and contains a sequence for RNA replicase, in addition to the coding sequence for the protein.

Transforming mRNA therapeutics into clinical realities requires easy and fast access to synthetic DNA in the design-build-test-learn iteration cycle. This is one of the rate-limiting steps that ...

A new discovery about mutations in a gene that causes ALS may allow researchers to design targeted therapies, a study found.

The Nobel Prize-winning technology underpinning COVID-19 vaccines is also fueling a host of biotechs developing treatments ...