Medscape3d
Bioequivalence and Rapid Absorption of Zolmitriptan Nasal Spray Compared With Oral Tablets in Healthy Japanese Subjects
Background and Objective: Oral zolmitriptan is highly effective in the acute treatment of migraine. However, nausea and vomiting during attacks may limit the usefulness of oral medications.
Medscape15d
Bioequivalence and Rapid Absorption of Zolmitriptan Nasal Spray Compared With Oral Tablets in Healthy Japanese Subjects
Zolmitriptan was detectable in plasma 2 minutes after intranasal administration in 75% (18/24) of subjects receiving the 2.5mg dose and in 79% (19/24) of subjects receiving the 5mg dose.