Little is known about how the immune system prevents vesicular stomatitis virus (VSV) from entering the central nervous system (CNS) following infection through the natural subcutaneous route.

Additionally, antiviral treatments that directly suppress EBV replication ... Epstein–Barr virus infection exacerbates ulcerative colitis by driving macrophage pyroptosis via the upregulation ...

To study this, they tested the impact of 80 different conditions—varying doses of six different bacterial and viral molecules—on macrophage activity using a high-throughput microfluidics ...

To test whether nSMase2 is essential for viral replication, the team inhibited the enzyme by ... New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and ...

The work, published in Science in an article titled, “Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae,” identifies how the viral infection damages ...

At the time of viral replication in the tumor ... secreted interferon-α (IFNα), secreted macrophage inflammatory protein-α (MIP1α) and membrane-bound CD80. Secreted MIP1α is a chemokine ...