News and Commentary Published: 22 July 2004 Salivary glands and gene therapy: the mouth waters R Zufferey & P Aebischer Gene Therapy 11, 1425–1426 (2004) Cite this article ...

In experiments in mice, when radiation destroys saliva-producing structures called acini, the animals' stem cells divide and differentiate into acinar cells to rebuild the salivary gland.

Munguia-Lopez, J. G., et al. (2025). Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels. International Journal of Oral Science ...

The damage to humans’ glands is permanent, but another species has the ability to rebuild the organ within two weeks of an injury. In experiments in mice, when radiation destroys saliva-producing ...

The former had epithelial types belonging to the serous and mucous acini, salivary ducts, myoepithelial cells, and glia, besides ionocytes, fibroblasts, endothelial, and smooth muscle cells. There ...

This study demonstrates that by fine-tuning hydrogel composition, we can closely replicate the native environment of salivary acinar cells. Our AGHA-based platform not only supports long-term ...