Adenylosuccinate lyase (ADSL) deficiency is an inherited metabolic disorder that impairs purine metabolism. ADSL is a key enzyme in both the de novo synthesis and the purine nucleotide cycle, ...
Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function. A recent study ...
Cell metabolism is often thought of as the process of breaking down sugars to create energy, but the process also involves all the biosynthetic reactions necessary to sustain life. One of these ...
A newly identified link between purine metabolism and microglial morphology during brain development
Researchers at University of Tsukuba have discovered that an immunosuppressive drug affects microglia, the resident immune cells of the brain. In mouse models, the drug reduced levels of guanosine ...
Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function. A recent study ...
Parkinson’s disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function. A recent study ...
Researchers at University of Tsukuba have discovered that an immunosuppressive drug affects microglia, the resident immune ...
Gut microbiota capable of metabolizing uric acid and purines may play a key role in reducing gout diagnoses, and although the findings from new retrospective and prospective studies suggest key roles ...
Researchers recently discovered that patients with Parkinson's disease exhibit lower levels of uric acid and impaired energy recycling. It challenges previous beliefs about uric acid's role in the ...
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