Researchers at Rockefeller showed that this process is mediated by two enzymes: telomerase and the CST–Polα/primase complex.
Positive Phase 1a interim data released for ABI-5366, a long-acting HSV helicase-primase inhibitor candidate for recurrent genital herpes, supporting potential for once-weekly and once-monthly ...
How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is to find proteins that directly bind to both enzymes.
Primase, eine an der DNA-Synthese (Replikation) beteiligte spezifische RNA-Polymerase, die die Synthese eines kurzen RNA-Abschnitts katalysiert, der komplementär zu einem der DNA-Matrizenstränge ist.