The effects and risks of the use of intravenous thrombolysis between 4.5 and 24 hours after the onset of a posterior circulation ischemic stroke are not well studied. In a trial conducted in China ...

In the Phase III EXPECTS trial, patients experiencing mostly mild posterior circulation ischemic stroke who were ineligible ...

Researchers found that the percentage of patients with functional independence at 90 days was higher in the alteplase group vs the standard treatment group. HealthDay News — For patients with ...

Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. New research findings are summarized in a short video.

but there was no reduction in stroke in the basilar artery territory or benefit for vertebral artery stenosis or posterior circulation disease in general. Results of ongoing prospective randomized ...

Stroke is the third leading cause of death ... The PCA is a part of the posterior circulation and arises from the basilar artery. The PCA supplies inferior parts of occipital and temporal lobes ...

primarily because it was underpowered and none of the patients in either group had experienced a posterior circulation stroke by the 8-year follow-up. In addition, maximal medical therapy was ...

For patients with mainly mild posterior circulation ischemic stroke, alteplase administered at 4.5 to 24 hours after onset results in higher frequency of functional independence.

More information: Shenqiang Yan et al, Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2413344 Journal ...

F RIDAY, April 4, 2025 (HealthDay News) -- For patients with mainly mild posterior circulation ischemic stroke who do not receive thrombectomy, alteplase administered at 4.5 to 24 hours after ...