Medically reviewed by Richard N. Fogoros, MD Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease that develops when ...

Medically reviewed by Laura Campedelli, DPT Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, potentially life-threatening disorder. It causes the red blood cells to break apart, a process ...

Signs of left heart failure such as paroxysmal nocturnal dyspnea and orthopnea can occur. Symptoms of heart failure with concomitant mitral stenosis also occur in disease states that require an ...

The mainstay of therapy for the rare blood disease paroxysmal nocturnal ... survive for decades with only minor symptoms. Somewhere between 20% and 50% of PNH patients treated with Soliris or ...

Somewhere between 20% and 50% of PNH patients treated with Soliris or other drugs in the C5 inhibitor class can't get symptoms under ... and rare kidney diseases C3 glomerulopathy (C3G) and ...