THE scientists plotting the return of the great Woolly Mammoth have successfully used gene editing technology to create a new Woolly Mouse. The extraordinary, palm-sized creature has had its DNA ...

When they exposed their ears to different allergens, the ears of the control mice, which scratched their itch, grew thick from inflammation within a day. In contrast, the ears of the mutant mice ...

One advantage of using G1 mice with an F1 hybrid background (an F1 hybrid is the offspring of two different inbred lines) is that the G2 progenies obtained from the backcrosses between a mutant ...

A mutation in this gene greatly increases the risk of colorectal cancer. One set of mice had a copy of the mutant APC gene ...

Polyglutamine (polyQ) diseases, a group of dominantly inherited CNS disorders, are caused by an abnormal expansion of ...

Fortunately, two of my colleagues at the Jackson Laboratory were using parabiosis to characterize anemia mutant mice and were pleased to instruct me in this technique. Parabiosis requires the ...

Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had ...