Key steps in the life cycle of HCV include entry into the host cell, uncoating of the viral genome, translation of viral proteins, viral genome replication, and the assembly and release of virions.

Occult HCV and HBV infections are recently identified ... These long-term silent infections are consequences of persistent low-level viral replication progressing in hepatocytes as well as in ...

HCV cannot be grown in culture and will not infect convenient laboratory animals, so little is known of the molecular mechanisms of viral replication, and even less is known about the dynamics of ...

Finally, although HCV is an RNA virus that does not produce DNA replication intermediates that can integrate into the host genome, it still manages to persist in most cases (usually for life in ...

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development. The introduction ...