This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

For the first time, researchers have filmed in real time the disassembly of DNA at the atomic scale. This strand separation ...

Scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands. As the helicase moves along the DNA ...

Using cryo-electron microscopy and deep learning to observe the helicase Simian Virus 40 Large Tumor Antigen interacting with DNA, the laboratories of KAUST Assistant Professor Alfredo De Biasio ...

IDEAYA Biosciences, Inc. (Nasdaq: IDYA), a leading precision medicine oncology company, today announced the publication of ...

Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being unzipped at the atomic level. The movie ...

MOMA Therapeutics, a clinical-stage biopharmaceutical company discovering and developing a new generation of precision ...

Using cutting edge cryo-electron microscopy, the team of scientists were able to visualise a helicase enzyme (nature's DNA unzipping machine) in the process of unwinding DNA. DNA helicases are ...

By binding uniquely to the helicase domain of WRN, IDE275 (GSK959) delivers potent and selective inhibition across MSI-H models," said Michael White, Ph.D., Chief Scientific Officer, IDEAYA ...