Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

Bier’s group previously exploited this mutation to develop a gene editing tool, called a gene drive, that reverted the mutated ion channel in a fruit fly model back to the wild type version. 2 Gene ...

In a recent study posted to the preprint server Research Square* while under review for publication in Epigenetics & Chromatin, researchers develop and characterize a highly specific EpiEditing system ...

In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...

In a recent study published in the journal Nature, an international team of researchers developed a novel approach to infer parent-of-origin (PofO) of alleles without parental genomes. Genome-wide ...