The cells in human bodies are subject to both chemical and mechanical forces. But until recently, scientists have not ...

Fibrosis is an affliction wherein cells produce excess fibrous tissue. Fibroblast cells do this to close wounds, but the process can cascade in unwanted places. Examples include cardiac fibrosis; ...

Biomedical researchers at Washington University in St. Louis have decoded how mechanical forces drive cell behavior in fibrosis.

If someone asked about fibroblasts, the response was that they thought they'd been relegated to the evolutionary scrap of connective tissue. They thought of fibroblasts’ simply as a structural ...

Fibroblasts, primary cells for the secretion and maintenance of connective tissue, secrete bioactive molecules such as growth factors, cytokines, and extracellular vesicles that influence cellular ...

Stopping cell microtubule protrusions, pictured here, could potentially inhibit unwanted fibrosis, wherein cells produce ...