The common gamma-chain cytokines signal through cytokine receptors that consist of the common cytokine receptor γ chain (γc/CD132/IL2RG). This family includes at least six short-chain cytokines: IL2, ...

Upon binding to their surface receptors, cytokines trigger downstream signaling cascades associated with many cellular processes, such as differentiation, tissue repair, proliferation, migration, and ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy.

IL17 is part of a cytokine family that includes five other members: IL17B, IL17C, IL17D, IL17E/IL25 and IL17F. The sequences of IL17 and IL17F are the most similar. To signal through the receptor ...

Toll-like receptor 4 activation consequently produces an innate immune response in the brain that initiates the release of glial-derived neuroexcitatory and neurotoxic substances such as ...

Siltuximab effectively treated patients who experienced common adverse events after chimeric antigen receptor T-cell therapy, ...

Cytokine and chemokine production was measured ... Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune ...