Also, can No. 4 Mississippi validate its win over LSU with another one as an underdog at No. 21 Florida or are the Gators really good; is No. 17 Iowa's offensive improvement fool's gold or will it get shut down at No.

Considered the favorite out of the Big Ten this preseason, one college football contender already has one very concerning loss heading into a ranked conference matchup this weekend.

From a high-stakes Group of Six showdown in Kalamazoo to massive tests for contenders like Texas, USC and LSU, these matchups will reshape the postseason picture