Collateral circulation is a potent predictor of revascularization and clinical outcomes after acute ischemic stroke ... from 369 cases of acute stroke with anterior circulation ischemia ...

Blood flow through the extracranial and intracranial systems decreases, and the collateral circulation ... in the ischemic cascade, forming the theoretical basis for many of the acute stroke ...

We recruited patients with acute posterior circulation ischemic stroke ... for extended-window IVT largely focuses on anterior circulation stroke with large-vessel occlusion and usually requires ...

For patients with mainly mild posterior circulation ischemic stroke who ... acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work ...

Blood is supplied to the brain by two major sets of arteries, the anterior ... cerebral circulation that may be extremely important in maintaining tissue viability during acute stroke.

In the Phase III EXPECTS trial, patients experiencing mostly mild posterior circulation ischemic stroke who were ineligible ...

For patients with posterior circulation stroke, alteplase administered at 4.5 to 24 hours after onset increases frequency of functional independence.

Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. New research findings are summarized in a short video.

Researchers found that the percentage of patients with functional independence at 90 days was higher in the alteplase group vs the standard treatment group. HealthDay News — For patients with ...

More information: Shenqiang Yan et al, Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours, New England Journal of Medicine (2025). DOI: 10.1056/NEJMoa2413344 Journal ...