Brady Cook’s Missouri Tigers are gearing up for an SEC matchup with the South Carolina Gamecocks in Week 12. The star quarterback has been listed as doubtful on the team’s injury report, however, after missing last weekend’s Oklahoma game with a wrist injury.

The offense side has been dealing with other important lingering injuries, including those to quarterback Brady Cook, running back Nate Noel and wide receiver Mookie Cooper. Health will be key for Missouri in what will likely be its final ranked matchup of the season at No.

What does Missouri football have to play for after its late loss at South Carolina? Starting quarterback Brady Cook has — and is — the answer.

Former Notre Dame and Arizona State QB Drew Pyne filled in for Cook against Oklahoma. The transfer did well enough, completing 14 of 27 passes for 143 yards with 3 TDs and no interceptions. If Cook can’t go, Pyne should be expected to fill in once again.

The battle for this year's Mayor's Cup between the South Carolina Gamecocks and Missouri has not disappointed. In a back and forth low-scoring affair to start t

South Carolina jarred Missouri in a slobberknocker of an SEC contest on Saturday, 34-30. The Tigers had taken the lead on a Brady Cook pass to Luther Burdern that was good for 37 yards with 1:10 left in the game.

One of just two matchups between top 25 ranked teams this Saturday will be played at Williams-Brice Stadium, as the 23rd-ranked Missouri Tigers will head to Columbia to take on the 21st-ranked South Carolina Gamecocks.